产品货号:
Z37767
中文名称:
Hu CD6 Purified抗体
英文名称:
Anti-Hu CD6 Purified Antibody (Clone#MEM-98)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Hu CD6 Purified Antibody (Clone#MEM-98) |
指标别名 | CD6;CD6 molecule;T12;TP120 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | FCM,IP,WB,IHC |
基因名称 | CD6 |
克隆号 | MEM-98 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Human CD6 antigen purified by immunoaffinity chromatography from HBP-ALL cells followed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gel corresponding to the 100kDa zone).The antibody MEM-98 reacts with an extracellular epitope of CD6,a 100~130kDa single chain transmembrane glycoprotein expressed on T and B lymphocytes subsets,thymocytes,and acute lymphocytic leukemia cells. |
计算分子量 | 72kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | CD6,also known as T12,is a member of the scavenger receptor superfamily found on T and B cell subsets,thymocytes,and acute lymphocytic leukemia cells (ALL).CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse.CD6-ALCAM mediated cell adhesion is also important for T cell proliferation.CD6 may exert some its functions via association with CD5,probably by fine-tuning CD5 signaling.Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells. |
Uniprot ID | P30203 |
基因名全称 | CD6 molecule |
蛋白名全称 | T-cell differentiation antigen CD6 |
推荐稀释比 | Flow cytometry:2μg/mL. Immunohistochemistry (paraffin sections):10μg/mL;positive tissue:spleen. Western blotting:Non-reducing conditions. |
相关搜索:Hu CD6 Purified抗体,Hu CD6 Purified单抗,Anti-Hu CD6 Purified Antibody (Clone#MEM-98)